Poster Abstracts


Research has consistently identified executive function (EF) and adaptive behavior deficits in children with Fragile X syndrome (FXS), a single-gene, neurodevelopmental disorder. However, no work has determined the association between parent-rated EF and adaptive behavior in 7 – 12 year-olds with FXS as we do in this study. Participants included 16 children with FXS (6 females: M(SD) age= 8.8 (0.8) years; 10 males: M(SD) age= 10.1 (1.0) years). Parents completed the Behavior Rating Inventory of Executive Function- Preschool Version (BRIEF-P), consistent with participants’ developmental level given co-occurring intellectual disability. The BRIEF-P assesses five EF domains: Inhibit, Shift, Emotional Control, Working Memory, Plan/Organize). Adaptive behavior was assessed using the Vineland Adaptive Behavior Scales- Second Edition (VABS-II) across: Daily Living Skills, Communication, Socialization, and Motor Skills domains. Spearman’s correlation results revealed significant negative associations (p<.01) between Shift and Motor Skills (r= -.76) and Socialization (r= -.78) domains; Plan/Organize and Motor Skills (r= -.59), Communication (r= -.53), and Socialization (r= -.55) domains; and Inhibit and Communication (r= -.54). Findings indicate that greater EF impairments are related to lower adaptive behavior skills in children with FXS. Thus, interventions targeting EF may also lead to improvements in adaptive bx.

First AuthorErin Hunt
Second AuthorElizabeth Will
Third AuthorJane Roberts