Poster Abstracts


Awake craniotomy with intraoperative mapping can minimize the risk of language morbidity from surgery; however, recoverability of language complications is not well understood. Using the Quick Aphasia Battery (QAB), we examined acute versus subacute (24-hour versus 2-week post-operation) language changes in a consecutive series of brain tumor patients undergoing surgery to known eloquent areas (n=24). To assess individual change, we used a reliable change index score of 0.8 derived from a sample of chronic stroke patients with aphasia, corresponding to a 95% confidence interval. 8 (33%) of 24 patients showed significant decline in their QAB score at 24 hours post-operation. 7 of them (86%) demonstrated decline in real time language monitoring during surgery. Only 2 (13%) of the 16 patients who did not decline on the QAB showed intraoperative language decline. When assessed 2 weeks post-operation, 6 (75%) of the 8 patients who initially declined on the QAB showed complete recovery, while the remaining 2 showed significant improvement but not quite back to their baseline. In conclusion, despite a high rate of acute post-operative language changes, most patients demonstrated significant improvement by two weeks from surgery and intraoperative monitoring can accurately identify patients at risk for identifying language complications.

First AuthorJun Min Koay
Second AuthorKaisorn L. Chaichana
Third AuthorAlfredo QuiƱones-Hinojosa
Fourth AuthorErik H. Middlebrooks
Fifth AuthorLina C. Marenco Hillembrand
Sixth AuthorDavid S. Sabsevitz