Chronic bilirubin encephalopathy (CBE) occurs due to extended bilirubin toxicity with widespread ramifications for neurological injury. CBE can result in significant neurodevelopmental difficulties for both full- and near-term infants. However, scarce information exists on particular neurocognitive outcomes of this rare condition (1/40,000). As such, a case presenting a neurocognitive profile of CBE in a pediatric patient who presented for neuropsychological testing is reported in hopes of elucidating consequential deficits. This case uses a clinical interview with parents and review of available medical records as part of a comprehensive neuropsychological evaluation for a six-year-old left-handed African-American patient with complex multifactorial premorbid medical and developmental history (jaundice, abnormal motor control, oculomotor impairment, enamel dysplasia), early therapy (speech, occupational and physical), and cognitive difficulties (attention and executive functioning). Primary deficits on testing were observed on tasks of verbal reasoning, naming, visuomotor functioning, attention (auditory and visual), and language. Nonverbal reasoning, learning and memory, academic skills and adaptive functioning was intact. The key elements in preventing CBE are risk assessment and appropriate follow-up. Little is known regarding the neurocognitive outcomes of CBE. This study highlights the need to consider the longitudinal impact for development and bridge the gaps in the available literature.
|First Author||Aamir Laique|
|Second Author||Llana Reife|
|Third Author||Hannah VanLandingham|
|Fourth Author||Humza Khan|
|Fifth Author||Rachael L. Ellison|