Poster Abstracts

Abstract

The lateralizing value of neuropsychological data remains an important topic, yet prior research has yielded mixed findings in differentiating right temporal lobe epilepsy (RTLE) from left temporal lobe epilepsy (LTLE). The current study retrospectively analyzed archival data to examine the predictive utility of neuropsychological tests in 45 RTLE patients (mean age=38.16 years, SD=12.00) and 63 LTLE patients (mean age=38.52 years, SD=11.31) diagnosed with long-term video EEG monitoring with neuroimaging evidence of temporal lobe structural abnormalities. Two tailed t-tests and chi-square analyses were conducted. RTLE subjects had significantly greater education (mean=14.00 years, SD=2.35) than LTLE subjects (mean=12.90 years, SD=2.15). LTLE patients performed significantly worse on immediate recall (p<.001), delayed recall (p<.001), and recognition (p=.008) trials of the Rey Auditory Verbal Learning Test (RAVLT) as well as letter verbal fluency (p=.003). Conversely, RTLE patients’ worse performance trended toward statistical significance on the Ruff Figural Fluency Test (RFFT) (p=.051) and Wechsler Memory Scale 4th Edition Designs subtest (p=.09). Including education as a covariate, backward stepwise logistic regression model revealed that the RAVLT delayed recall, Visual Reproduction delayed recall, and RFFT error ratio scores explained 63.0% of the variance. These findings suggest that memory and figural fluency performances may improve neuropsychological predictions of lateralization.

First AuthorJoseph J. Boscarino
Second AuthorFerdinand Korneli
Third AuthorEmily N. Vanderbleek
Fourth AuthorMichael R. Schoenberg